Prognostic Indicators in Choroidal and Ciliary Body Melanoma
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منابع مشابه
Metastatic melanoma death rates by anatomic site after proton beam irradiation for uveal melanoma.
BACKGROUND Ciliary body location is an established prognostic factor for metastasis-related death from uveal melanoma. We evaluated alternative approaches for classifying this covariate when constructing predictive models of patient survival. METHODS AND DESIGN The analyses were based on a consecutive series of 1848 primary choroidal and/or ciliary body melanoma patients treated with proton b...
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Purpose The most common malignant intraocular tumors with a high mortality in adults are uveal melanomas. Uveal melanomas arise most frequently in the choroid or ciliary body (97%) and rarely in the iris (3%). Whereas conjunctival and posterior uveal (ciliary body and choroidal) melanomas have been studied in more detail genetically, little data exist regarding iris melanomas. Methods In our ...
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OBJECTIVE To evaluate whether nuclear activity as measured by the disodium phosphate 32P (32P) uptake test for uveal melanoma is of prognostic value and corresponds to known prognostic factors. METHODS A retrospective analysis of 121 patients with choroidal and/or ciliary body melanoma, tested with the 32P uptake test before enucleation between January 1, 1973, and December 31, 1976, at the L...
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BACKGROUND Bcl-2 protooncogene alterations are involved in tumorigenesis and may have prognostic ramifications. AIMS To investigate normal ocular structures and choroidal melanoma for: (1) Bcl-2 protein expression (semiquantitative staining values: SI, staining intensity; PP, percentage of positive cells; and IRS, immunoreactivity score) and (2) any associations between the staining values an...
متن کاملMicrovascular density in predicting survival of patients with choroidal and ciliary body melanoma.
PURPOSE Although malignant uveal melanoma disseminates predominantly hematogenously because of the absence of intraocular lymphatics, consensus about prognostic impact of microvascular density (MVD) has not been reached. This study was undertaken to investigate whether MVD, microvascular patterns, or both determine prognosis of uveal melanoma. METHODS A population-based retrospective cohort s...
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تاریخ انتشار 2001